Bioactive Glass Content

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BioSphere® Putty Composition

• Weight:  ~80% bioactive glass spheres; ~20% phospholipid carrier

• Volume:  95-100% of the bulk volume consists of bioactive glass spheres (carrier fills up the volume in between particles)

• Bioactive Glass Concentration:  ~1.5 g of bioactive glass per cc of Putty 

 Comparison to Bioactive Glass Bone Graft Sheets

• Sheets are composed of bioactive glass particles that are suspended in a porous scaffold (typically composed of collagen)

• Due to porosity, bone graft sheets have a much lower density (0.25 - 0.40 g/cc) than BioSphere® Putty (~1.9g/cc)

• Bioactive glass concentration (grams of bioactive glass per cc of graft) is the accurate way of comparing bioactive glass content.

BioSphere® Putty has the highest bioactive glass content of any bone graft putty or sheet on the market.

10cc of BioSphere® 
putty (1.5g/cc; 80% bioactive glass) contains 
~15g of bioactive glass

vs.

10cc of a bone graft
sheet (0.4 g/cc; 88% bioactive glass) contains 
~3.5g of bioactive glass

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Close-up of Synergy's
BioSphere® Putty 
showing high bioactive glass sphere content