Bioactive Glass Content

BioSphere® Putty Composition
  • Weight:  ~80% bioactive glass spheres; ~20% phospholipid carrier

  • Volume:  95-100% of the bulk volume consists of bioactive glass spheres (carrier fills up the volume in between particles)

  • Bioactive Glass Concentration:  ~1.5 g of bioactive glass per cc of Putty 


 Comparison to Bioactive Glass Bone Graft Sheets
  • Sheets are composed of bioactive glass particles that are suspended in a porous scaffold (typically composed of collagen)

  • Due to porosity, bone graft sheets have a much lower density (0.25 - 0.40 g/cc) than BioSphere Putty (~1.9g/cc)

  • Bioactive glass concentration (grams of bioactive glass per cc of graft) is the accurate way of comparing bioactive glass content.

BioSphere® Putty has the highest bioactive glass content of any bone graft putty or sheet on the market.
10cc of BioSphere 
putty (1.5g/cc; 80% bioactive glass) contains 
~15g of bioactive glass

vs.

10cc of a bone graft
sheet (0.4 g/cc; 88% bioactive glass) contains 
~3.5g of bioactive glass
Close-up of Synergy's
BioSphere Putty 
showing high bioactive glass sphere content