Based on the effects that shape and size have on the ability of bioactive glass to form bone, Synergy has developed an optimal bioactive glass particle with a spherical shape.  Synergy's BioSphere particles have been further optimized into a bimodal size distribution to maximize the bone healing potential of 45S5 bioactive glass.

Synergy utilizes a unique spherical form of 45S5 bioactive glass in its bone graft products. These particles have the ability to form a calcium phosphate coating when implanted in vivo which improves the ability of the graft to support bone formation on its surface.

BioSphere® Putty utilizes Synergy's unique spherical bioactive glass particles and a phospholipid carrier to create a moldable bone graft putty with improved bone formation.